Join us for “Potassium channel structural dynamics landscape" a keynote presentation by Dr. Marcos Matamoros Campos, School of Medicine, Medical Pharmacology and Physiology, Biochemistry MizzouForward faculty candidate.  Dr. Matamoros Campos will present on his research for approximately 40-minutes with a 20-minute question and answer session to follow.

Dr. Matamoros Campos is a researcher who is working in an interdisciplinary frontier involving biophysics, physiology, and structural biology of membrane proteins. Since his early undergraduate experience, he has developed a fascination with how ion channels and membrane proteins work, what happens when they function abnormally, and how we can modulate their behavior. His graduate studies provided him with a strong foundation in ion channel physiology and honed his ability to dissect complex mechanistic questions concerning different Na+, Ca2+ and K+ channel gating, and pharmacology, mostly related with cardiac diseases under the supervision of Prof. Eva Delpón at Complutense University of Madrid.

Dr. Matamoros Campos sought to complement this experience with additional expertise in ion channel biochemistry, structure, and dynamics during my post-doctoral training. He identified Prof. Nichols at Washington University as an ideal mentor due to his extensive expertise in both the fields of biophysics and physiology. In the Nichols lab, he has led several projects to delineate the K+ channel structural dynamics basis of ion selectivity in bacterial and in mammalian K+ channels, using a combination of biochemistry, electrophysiology and fluorescence techniques that allowed me to record dynamic views of these membrane proteins. 

K+ channels are membrane proteins that allow rapid and exquisite selective flow of K+ ions across the cell membrane that is crucial to generate chemical and electrical activities in living cells, and their dysfunction led to many human diseases. To completely understand the behavior of ion channels, dynamic views of the structures are essential to fill the gap between crystal/CryoEM structures and single ion channel current analyses. The structural dynamics of potassium channel proteins presents an exciting and emerging field of study which will provide new understanding of the fundamental basis of channel function.    

You can access Dr. Matamoros Campo’s CV via OneDrive here:

 Matamoros_CV_2023.pdf (University log in required to access)

After the keynote, please provide candidate feedback with our brief survey.