MizzouForward Keynote – Quantitative dissection of genetic drivers in lung cancer

January 31st | 2:30pm – 3:30pm

Acuff Auditorium (MA217) – School of Medicine

Join us for “Quantitative dissection of genetic drivers in lung cancer" a keynote presentation by School of Medicine, MizzouForward faculty candidate, Dr. Rui Tang.  Dr. Tang will present on his research for approximately 40-minutes with a 20-minute question and answer session to follow.

Dr. Rui Tang is currently a Postdoctoral Scholar at Stanford University, Calfornia.  Dr. Tang completed his Bachelor of Science degree in Biology at Nanjing University, China and earned his Ph.D in Physiology from the University of Georgia.

Lung cancer is a prevalent cancer type that carries diverse genetic alterations. Identification of genetic drivers in lung cancer will deepen our understanding of cancer biology and inform the development of novel therapeutics. Dr. Tang has combined multiplexed somatic CRISPR/Cas9-based genome editing in genetically engineered mouse models with tumor barcoding and high-throughput barcode sequencing to uncover the impact of diverse KRAS-interacting proteins on lung cancer growth. Dr. Tang’s team’s study outlines a technological avenue to uncover positive and negative regulators of oncogenic KRAS-driven cancer in a multiplexed manner in vivo and highlights the role of the phenomenon they term RAS paralog imbalance in oncogenic KRAS-driven lung cancer. In parallel, he also developed technologies to record cancer-stroma interactions (G-baToN) and to deconvolute genotype-specific metastatic effect (Moba-seq). As a cancer biologist with an interdisciplinary background, Dr. Tang will leverage unique combinations of his expertise in vascular biology, quantitative cancer genetics, and cancer-stroma interactions to establish his research program to understand the metastatic microenvironment.

You can access Dr. Tang’s CV via OneDrive here:

 RuiTang_CV.pdf  (University log in required to access)

After the keynote, please provide candidate feedback with our brief survey.